Rupniak NMJ, Katofiasc MA, Bae J, Thor KB, Marson L: Colorectal and bladder prokinetic activity of [Lys5, MeLeu9, Nle10]-NKA(4-10) after intranasal or sublingual delivery in dogs. Can J Physiol Pharmacol. 2023 Apr 1;101(4):171-179. doi: 10.1139/cjpp-2022-0498. Epub 2023 Jan 30.PMID: 36716436
Cook JB, Piatt R, Marson L: [Lys5,MeLeu9,Nle10]-NKA(4-10) induces neurokinin 2 receptor mediated urination and defecation and neurokinin 1 receptor mediated flushing in rats: measured using the rapid detection voiding assay. J Basic Clin Physiol Pharmacol. 2022 Nov 16;34(2):227-233. doi: 10.1515/jbcpp-2022-0119. eCollection 2023 Mar 1.PMID: 36377965
Marson L, Piatt R, Cook JB, Thor KB: Neurokinin 2 receptor-mediated bladder and colorectal responses in aged spinal cord injured rats. Spinal Cord. 2021 Sep;59(9):1013-1017. doi: 10.1038/s41393-021-00684-8. Epub 2021 Aug 17.PMID: 34404911
Bourbeau D, Creasey G, French J, Grill WM, Howley S, Krassioukov A, Moritz C, Santacruz B, Thor K, Wheeler T.A: A roadmap for advancing neurostimulation approaches for bladder and bowel function after spinal cord injury. Spinal Cord. 2020 Nov;58(11):1227-1232. doi: 10.1038/s41393-020-00544-x. Epub 2020 Sep 7.PMID: 32895476
Bourbeau D, Bolon A, Creasey G, Dai W, Fertig B, French J, Jeji T, Kaiser A, Kouznetsov R, Rabchevsky A, Santacruz BG, Sun J, Thor KB, Wheeler T, Wierbicky J: Needs, priorities, and attitudes of individuals with spinal cord injury toward nerve stimulation devices for bladder and bowel function: a survey. Spinal Cord. 2020 Nov;58(11):1216-1226. doi: 10.1038/s41393-020-00545-w. Epub 2020 Sep 7.PMID: 32895475
Marson L, Piatt RK 2nd, Katofiasc MA, Bobbitt C, Thor KB Chronic: Twice-Daily Dosing of an NK2 Receptor Agonist [Lys5,MeLeu9,Nle10]-NKA(4-10), Produces Consistent Drug-Induced Micturition and Defecation in Chronic Spinal Rats. J Neurotrauma. 2020 Mar 15;37(6):868-876. doi: 10.1089/neu.2019.6676. Epub 2019 Nov 13.PMID: 31642371
Perdona E, Cavallini P, Sava A, Griffante C, Ricca DJ, Thor KB, Rupniak NMJ, Corsi M: Potency, efficacy, and selectivity of GR64349 at human recombinant neurokinin NK2 and NK1 receptors. Neurosci Lett. 2019 Oct 15;711:134456. Epub 2019 Aug 22, PMID: 31445972
Rupniak NMJ, Katofiasc MA, Marson L, Ricca DJ, Thor KB, Burgard EC: Prokinetic effects of the neurokinin NK2 receptor agonist [Lys5,MeLeu9,Nle10]-NKA(4-10) on bladder and colorectal activity in minipigs. Neuropeptides. 2019 Oct;77:101956. Epub 2019 Jul 11, PMID: 31324387
Bae J, Johnston TA, Chaiittianan R, Sutthanut K, Jay M, Marson L: Characterization and in vivo efficacy of a heptapeptide ODT formulation for the treatment of neurogenic bladder dysfunction. Int J Pharm. 2018 Jan 30;536(1):397-404. Epub 2017 Nov 28. PMID: 29195918
Rupniak NMJ, Perdona E, Griffante C, Cavallini P, Sava A, Ricca DJ, Thor KB, Burgard EC, Corsi M: Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors. PLoS One, 2018 Oct 25;13(10):e0205894, PMID: 30359406
Rupniak NMJ, Katofiasc M, Burgard EC, Thor KB: Colorectal and cardiovascular effects of [Lys5,MeLeu9,Nle10]-NKA(4-10) in anesthetized macaques. Naunyn Schmiedebergs Arch Pharmacol. 2018 Jun 1, PMID: 29858647
Rupniak NMJ, Katofiasc M, Walz A, Thor KB, Burgard EC: [Lys5,MeLeu9,Nle10]-NKA(4-10) Elicits NK2 Receptor-Mediated Micturition and Defecation, and NK1 Receptor-Mediated Emesis and Hypotension, in Conscious Dogs. J Pharmacol Exp Ther. 366:136-144, 2018.
Rupniak NMJ, Katofiasc M, Marson L, Thor KB: NK2 and NK1 receptor-mediated effects of NKA and analogs on colon, bladder, and arterial pressure in anesthetized dogs. Naunyn Schmiedebergs Arch Pharmacol. 391:299-308, 2018.
Marson L, Thor KB, Katofiasc M, Burgard EC, Rupniak NMJ: Prokinetic effects of neurokinin-2 receptor agonists on the bladder and rectum of rats with acute spinal cord transection. Eur J Pharmacol. 819:261-269, 2018.
Alexander M, Bashir K, Alexander C, Marson L, Rosen R.: A randomized trial of clitoral vacuum suction and vibratory stimulation in neurogenic female orgasmic dysfunction. Archives of Physical Medicine and Rehabilitation. 2017 Sep 9. doi: 10.1016/j.apmr.2017.09.001.
Alexander MS, Marson L.: The neurologic control of arousal and orgasm with specific attention to spinal cord lesions: Integrating preclinical and clinical sciences. Autonomic Neuroscience: Basic and Clinical Jan 25. doi: 10.1016/j.autneu.2017.01.005.
Kullmann FA, Katofiasc M, Thor KB, Marson, L.: Pharmacodynamic evaluation of Lys5, MeLeu9, Nle10NKA(4–10) prokinetic effects on bladder and colon activity in acute spinal cord transected and spinally intact rats. Naunyn-Schmiedeberg’s Arch Pharmacol. 2017 Feb;390(2):163173. PMID: 27889808.
Kullmann FA, Kurihara R, Ye L, Wells GI, McKenna DG, Burgard EC, Thor KB: Effects of the 5-HT4 receptor agonist, cisapride, on neuronally evoked responses in human bladder, urethra, and ileum. Auton Neurosci. 2013 Jun;176(1-2):70-7. PMID: 23511063.
Burgard EC, Fraser MO, Karicheti V, Ricca DJ, Thor KB: New pharmacological treatments for urinary incontinence and overactive bladder. Curr Opin Investig Drugs. 2005 Jan;6(1):81-9. PMID: 15675607.
deGroat WC, Kawatani M, Hisamitsu T, Cheng CL, Ma CP, Thor KB, Steers W, Roppolo JR: Mechanisms underlying the recovery of urinary bladder function following spinal cord injury. J Autonom Nerv Syst 30: S71-S78, 1990. PMID: 2212495.
Thor KB, Roppolo JR, Kawatani M, Erdman S, deGroat WC: Plasticity in spinal opioid control of lower urinary tract function in paraplegic cats. Neurorept 5: 1673-1678, 1994. PMID: 7819545.
Thor KB, Katofiasc MA: Effects of duloxetine a combined serotonin and norepinephrine re-uptake inhibitor on central neural control of lower urinary tract function in the chloralose-anesthetized female cat. J Pharmacol Exp Ther 274: 1014-1024, 1995. PMID: 7636716.
Ashburn TT, Thor KB: Drug repositioning: identifying and developing new uses for existing drugs. Nature Reviews. Drug Discovery 3:673-83, 2004. PMID: 15286734.
Gu B, Olejar KJ, Reiter JP, Thor KB, Dolber PC: Inhibition of bladder activity by 5-HT1 serotonin receptor agonists in cats with chronic spinal cord injury. J. Pharmacol. Expt. Ther. 310: 1266-72, 2004. PMID: 15152026.
Thor KB, de Groat WC: Neural control of the female urethral and anal rhabdosphincter and pelvic floor muscles. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299:R416-R438, 2010. PMID: 20484700.
Karicheti V, Langdale CL, Ukai M, Thor KB: Characterization of a “Spinal – Urine Storage Reflex – Inhibitory Center” (SUSRIC) and Its Regulation by Serotonin 5-HT1A Receptors in Female Cats. Am J Physiol Regul Integr Comp Physiol. 298: R1198-R1208, 2010. PMID: 20164207.
Marson, L.: Spinal control of sexual reflexes: An overview of studies from animal models. Topics In Spinal Cord Rehabilitation. 8:42-50 (2002).
Looney, C., Thor, K.B., Ricca, D. and Marson, L: Differential effects of simultaneous or sequential administration of paroxetine and WAY-100,635 on ejaculatory behavior. Pharmacology Biochemistry and Behavior. 82:427-433 (2005). PMID 16253317.
