Dignify Therapeutics

Representative publications by Dignify Scientists related to Bladder Function following Spinal Injury

1. Properties of urethral rhabdosphincter motoneurons and their regulation by noradrenaline.
Yashiro K, Thor KB, Burgard EC.
J Physiol. 2010 Dec 15;588(Pt 24):4951-67. doi:10.1113/jphysiol.2010.197319.
PMID: 20974682 [PubMed - indexed for MEDLINE] Free PMC Article
 
2. Neural control of the female urethral and anal rhabdosphincters and pelvic floor muscles.
Thor KB, de Groat WC.
Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R416-38. doi: 10.1152/ajpregu.00111.2010. Epub 2010 May 19. Review.
PMID: 20484700 [PubMed - indexed for MEDLINE] Free PMC Article
 
3. Characterization of a spinal, urine storage reflex, inhibitory center and its regulation by 5-HT1A receptors in female cats.
Karicheti V, Langdale CL, Ukai M, Thor KB.
Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1198-208. doi: 10.1152/ajpregu.00599.2009. Epub 2010 Feb 17.
PMID: 20164207 [PubMed - indexed for MEDLINE]
 
4. Effect of 5-hydroxytryptamine1 serotonin receptor agonists on noxiously stimulated micturition in cats with chronic spinal cord injury.
Gu B, Thor KB, Reiter JP, Dolber PC.
J Urol. 2007 Jun;177(6):2381-5.
PMID: 17509363 [PubMed - indexed for MEDLINE]
 
5. Activation of the external urethral sphincter central pattern generator by a 5-HT(1A) receptor agonist in rats with chronic spinal cord injury.
Dolber PC, Gu B, Zhang X, Fraser MO, Thor KB, Reiter JP.
Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1699-706. Epub 2007 Jan 4.
PMID: 17204596 [PubMed - indexed for MEDLINE]
 
6. Inhibition of bladder activity by 5-hydroxytryptamine1 serotonin receptor agonists in cats with chronic spinal cord injury.
Gu B, Olejar KJ, Reiter JP, Thor KB, Dolber PC.
J Pharmacol Exp Ther. 2004 Sep;310(3):1266-72. Epub 2004 May 19.
PMID: 15152026 [PubMed - indexed for MEDLINE] Free Article
 
7. Induction of bladder sphincter dyssynergia by kappa-2 opioid receptor agonists in the female rat.
Gu B, Fraser MO, Thor KB, Dolber PC.
J Urol. 2004 Jan;171(1):472-7.
PMID: 14665958 [PubMed - indexed for MEDLINE]
 
8. Regenerative urinary bladder augmentation using small intestinal submucosa: urodynamic and histopathologic assessment in long-term canine bladder augmentations.
Kropp BP, Rippy MK, Badylak SF, Adams MC, Keating MA, Rink RC, Thor KB.
J Urol. 1996 Jun;155(6):2098-104.
PMID: 8618344 [PubMed - indexed for MEDLINE]
 
9. Characterization of small intestinal submucosa regenerated canine detrusor: assessment of reinnervation, in vitro compliance and contractility.
Kropp BP, Sawyer BD, Shannon HE, Rippy MK, Badylak SF, Adams MC, Keating MA, Rink RC, Thor KB.
J Urol. 1996 Aug;156(2 Pt 2):599-607.
PMID: 8683741 [PubMed - indexed for MEDLINE]
 
10. Regenerative bladder augmentation: a review of the initial preclinical studies with porcine small intestinal submucosa.
Kropp BP, Badylak S, Thor KB.
Adv Exp Med Biol. 1995;385:229-35. Review. No abstract available.
PMID: 8571835 [PubMed - indexed for MEDLINE]
 
11. Plasticity in spinal opioid control of lower urinary tract function in paraplegic cats.
Thor KB, Roppolo JR, Kawatani M, Erdman S, deGroat WC.
Neuroreport. 1994 Aug 15;5(13):1673-8.
PMID: 7819545 [PubMed - indexed for MEDLINE]
 
12. Selective inhibitory effects of ethylketocyclazocine on reflex pathways to the external urethral sphincter of the cat.
Thor KB, Hisamitsu T, Roppolo JR, Tuttle P, Nagel J, deGroat WC.
J Pharmacol Exp Ther. 1989 Mar;248(3):1018-25.
PMID: 2539452 [PubMed - indexed for MEDLINE]
 
13. Naloxone induced micturition in unanesthetized paraplegic cats.
Thor KB, Roppolo JR, deGroat WC.
J Urol. 1983 Jan;129(1):202-5.
PMID: 6681849 [PubMed - indexed for MEDLINE]
 
14. Effects of clonidine on the lumbar sympathetic pathways to the large intestine and urinary bladder of the cat.
Krier J, Thor KB, de Groat WC.
Eur J Pharmacol. 1979 Oct 26;59(1-2):47-53.
PMID: 510399 [PubMed - indexed for MEDLINE]